CFAP99 (Cilia and Flagella Associated Protein 99)

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Cilia and flagella of eukaryotes

As recognized by Irene Manton (1) at the time that the basic 9 + 2 structural uniformity of cilia and most eukaryotic flagella was first becoming recognized, these organelles are sufficiently complex that knowledge of their structure, no matter how detailed, cannot provide an understanding of their mechanisms of growth and function . In our understanding of these mechanisms, the substantial adv...

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Cilia and Flagella of Eukaryotes

As recognized by Irene Manton (1) at the time that the basic 9 + 2 structural uniformity of cilia and most eukaryotic flagella was first becoming recognized, these organelles are sufficiently complex that knowledge of their structure, no matter how detailed, cannot provide an understanding of their mechanisms of growth and function . In our understanding of these mechanisms, the substantial adv...

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Cilia- and Flagella-Associated Protein 69 Regulates Olfactory Transduction Kinetics in Mice.

Animals detect odorous chemicals through specialized olfactory sensory neurons (OSNs) that transduce odorants into neural electrical signals. We identified a novel and evolutionarily conserved protein, cilia- and flagella-associated protein 69 (CFAP69), in mice that regulates olfactory transduction kinetics. In the olfactory epithelium, CFAP69 is enriched in OSN cilia, where olfactory transduct...

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Nonlinear dynamics of cilia and flagella.

Cilia and flagella are hairlike extensions of eukaryotic cells which generate oscillatory beat patterns that can propel micro-organisms and create fluid flows near cellular surfaces. The evolutionary highly conserved core of cilia and flagella consists of a cylindrical arrangement of nine microtubule doublets, called the axoneme. The axoneme is an actively bending structure whose motility resul...

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Making sense of cilia and flagella

Data reported at an international meeting on the sensory and motile functions of cilia, including the primary cilium found on most cells in the human body, have thrust this organelle to the forefront of studies on the cell biology of human disease.

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ژورنال

عنوان ژورنال: Atlas of Genetics and Cytogenetics in Oncology and Haematology

سال: 2018

ISSN: 1768-3262

DOI: 10.4267/2042/68171